2020 Employee Stock Purchase Plan Two Thousand Twenty Employee Stock Purchase Plan [Member] Two thousand twenty employee stock purchase plan. Initial funding committed by award Initial Funding Committed By Award Initial funding committed by award. Collaborative Arrangement and Arrangement Other than Collaborative Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Document Transition Report Document Transition Report Expected volatility Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate Weighted-Average Remaining Contractual Term (Years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Money Market Funds Money Market Funds [Member] Computers and Computer Software Computers And Computer Software [Member] Computers and computer software. Vesting period for stock options granted Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period Total Investments, Fair Value Debt Securities, Available-for-Sale Agreement expiration date. Agreement Expiration Date Agreement expiration date Other Liabilities, Noncurrent, Total Other liabilities Other Liabilities, Noncurrent Increase (Decrease) in Prepaid Expense and Other Assets, Total Prepaid expenses and other current assets Increase (Decrease) in Prepaid Expense and Other Assets Restricted stock units outstanding Restricted Stock Units (RSUs) [Member] Restricted Stock Units Level 1 Fair Value, Inputs, Level 1 [Member] Fair Value Measurements and Fair Value of Financial Instruments Fair Value Disclosures [Text Block] Additional Facility Additional Facility [Member] Additional facility. Grant receivable Grants Receivable, Current Funding Arrangement [Line Items] Funding Arrangement [Line Items] Funding arrangement. Schedule Of Organization Consolidation And Presentation Of Financial Statements [Table] Schedule Of Organization Consolidation And Presentation Of Financial Statements [Table] Schedule of organization consolidation and presentation of financial statements. Fair value assets transferred into level 3 Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset Transfers Into Level 3 Series D Redeemable Convertible Preferred Stock Series D Redeemable Convertible Preferred Stock [Member] Series D redeemable convertible preferred stock. Summary of Stock-based Compensation Expense Share-Based Payment Arrangement, Cost by Plan [Table Text Block] Subsequent Events Subsequent Events [Text Block] Issuance of common stock to Lonza Ltd. (in shares) Number of common stock issued Stock Issued During Period, Shares, Issued for Services Accrued manufacturing expenses Accrued Manufacturing Expenses Accrued manufacturing expenses. Options and Restricted Stock Units Available for Grant, forfeited Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant Forfeited In Period Share-based compensation arrangement by share-based payment award number of shares available for grant forfeited in period. Net proceeds from follow on offering Proceeds from Issuance follow on offering Proceeds from issuance follow on offering. Total assets measured at fair value, Amortized Cost Cash And Cash Equivalents And Investments Amortized Cost Basis Cash and cash equivalents and investments amortized cost basis. Non-current operating lease liabilities Operating lease liabilities — long-term Operating Lease, Liability, Noncurrent Schedule Of Stock By Class [Table] Schedule of Stock by Class [Table] Vesting of early exercised stock options Adjustments To Additional Paid In Capital Vesting Of Early Exercised Stock Options Adjustments to additional paid In capital vesting of early exercised stock options. Lonza Commercial Manufacturing and Supply Agreement Lonza Commercial Manufacturing and Supply Agreement [Member] Lonza commercial manufacturing and supply agreement. Assets: Assets, Fair Value Disclosure [Abstract] Class of Stock [Line Items] Class of Stock [Line Items] Balance Sheet Location Balance Sheet Location [Axis] Sutro Biopharma Inc [Member] Sutro Biopharma, Inc. Sutro Biopharma Inc Total current assets Assets, Current Options and Restricted Stock Units Available for Grant, exercised Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant Exercised In Period Share-based compensation arrangement by share-based payment award number of shares available for grant exercised in period. Prefunded Warrants Price Per Share Prefunded Warrants Price Per Share Prefunded warrants price per share. Total liabilities and stockholders' equity Liabilities and Equity Entity Address, State or Province Entity Address, State or Province Issuance of common stock upon initial public offering or at-the-market offering, net of issuance costs Stock Issued During Period, Value, New Issues Issuance of common stock, value Number of shares outstanding Number of Options, Beginning Balance Number of Options, Ending Balance Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Release of restricted stock units, shares Release of Restricted Stock Units Shares Release of Restricted Stock Units Shares Weighted-average grant date fair value of options granted Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Comprehensive loss Comprehensive Income (Loss), Net of Tax, Attributable to Parent Trading Symbol Trading Symbol Common Stock, Shares, Issued, Total Common stock, shares owned Common stock, shares issued Common Stock, Shares, Issued Schedule of Cash, Cash Equivalents And Restricted Cash Restrictions on Cash and Cash Equivalents [Table Text Block] Schedule Of Organization Consolidation And Presentation Of Financial Statements [Line Items] Schedule Of Organization Consolidation And Presentation Of Financial Statements [Line Items] Schedule of organization consolidation and presentation of financial statements. 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Additional Milestone Payments in Cash Additional Milestone Payments in Cash Plan Name Plan Name [Domain] Accounting standard update adopted Change in Accounting Principle, Accounting Standards Update, Adopted [true false] Upfront consideration. Upfront Consideration Upfront Consideration Restricted cash Restricted Cash, Noncurrent Increase (Decrease) in Other Operating Assets, Total Other assets Increase (Decrease) in Other Operating Assets Operating lease, option to renewal, description Lessee, Operating Lease, Option to Extend Preferred Stock, Shares Outstanding, Ending Balance Preferred Stock, Shares Outstanding, Beginning Balance Preferred stock, shares outstanding Preferred Stock, Shares Outstanding Operating lease liabilities Increase Decrease In Operating Lease Liabilities Increase decrease in operating lease liabilities. Total current liabilities Liabilities, Current Entity Tax Identification Number Entity Tax Identification Number Palo Alto Palo Alto [Member] Palo alto. 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Proceeds from Stock Plans Proceeds from issuance of common stock under Employee Stock Purchase Plan Supplemental disclosure of cash flow information: Supplemental Cash Flow Information [Abstract] Nonvested Restricted Stock Shares Activity Nonvested Restricted Stock Shares Activity [Table Text Block] Accumulated Deficit Retained Earnings [Member] Class of Stock Class of Stock [Axis] Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number Ending Balance Beginning balance Ending balance Beginning balance Lease Incentives Lease Payment Receivable Noncurrent Lease Payment Receivable Noncurrent Gain (Loss) on Disposition of Assets, Total Loss on disposal of fixed assets Gain (Loss) on Disposition of Assets Stock Issued During Period, Shares, Employee Stock Purchase Plans Stock Issued During Period, Shares, Employee Stock Purchase Plans (in shares) Minimum Minimum Minimum [Member] Maximum commission percentage of gross proceeds from common stock sold Maximum Commission Percentage Of Gross Proceeds From Common Stock Sold Maximum commission percentage of gross proceeds from common stock sold. Schedule Of Information Related To Right Of Use Assets And Lease Liabilities Table [Text Block] Schedule of information related to right-of-use assets and lease liabilities. Schedule of Information Related to Lease Schedule of Contractual Maturities of Investments Investments Classified by Contractual Maturity Date [Table Text Block] Proceeds from exercise of common stock options Proceeds from Stock Options Exercised Schedule of Prepaid Expenses and Other Current Assets Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block] Operating lease liabilities Total lease liabilities Operating Lease, Liability Total lease liabilities Scenario Forecast Forecast [Member] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Table] Fair Value Measurement Inputs and Valuation Techniques [Table] Expected volatility, Minimum Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum U.S. Government Agency Securities US Government Agencies Debt Securities [Member] Equity Component Equity Component [Domain] Accounting standard update adoption date Change in Accounting Principle, Accounting Standards Update, Adoption Date Fair Value Assumptions Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions and Methodology [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Option exercise price in cash. Option Exercise Price in Cash Option Exercise Price in Cash Measurement Frequency Measurement Frequency [Axis] Entity Current Reporting Status Entity Current Reporting Status Common stock, shares authorized Common Stock, Shares Authorized Research and Development Expense, Total Research and Development Expense Research and development Assets Assets [Abstract] Proceeds from issuance of stock, net of commission and offering expenses Proceeds from Issuance of Common Stock Proceeds from issuance of common stock related to at-the-market offering, net of issuance costs Options and Restricted Stock Units Available for Grant, Ending Balance Options and Restricted Stock Units Available for Grant, Beginning Balance Aggregate number of shares available for issuance Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant Fair value on Date of Settlement. Fair Value on Date of Settlement Fair Value on Date of Settlement Interest receivable Interest Receivable, Current Common stock, $0.001 par value - 500,000,000 shares authorized at September 30, 2023 and December 31, 2022; 95,099,101 and 79,470,670 shares issued and outstanding at September 30, 2023 and December 31, 2022, respectively Common Stock, Value, Issued, Ending Balance Common Stock, Value, Issued, Beginning Balance Common Stock, Value, Issued, Total Common Stock, Value, Issued Funding Arrangement [Table] Funding Arrangement [Table] Funding arrangement. Proceeds from Sale of Property, Plant, and Equipment, Total Proceeds from sale of property and equipment Proceeds from Sale of Property, Plant, and Equipment Description of lease not yet commenced Lessee, Operating Lease, Lease Not yet Commenced, Description Furniture and Equipment Furniture and Fixtures [Member] Operating lease, extended term Lessee Operating Lease Extended Lease Term Lessee operating lease extended lease term. ATM Sales Agreement A T M Sales Agreement [Member] ATM sales agreement. Accrued expenses Total Accrued Liabilities, Current Current Fiscal Year End Date Current Fiscal Year End Date Share-based Payment Arrangement, Noncash Expense, Total Stock-based compensation expense Share-Based Payment Arrangement, Noncash Expense Loss from operations Operating Income (Loss) ASU 2019-12 Accounting Standards Update 2019-12 [Member] Entity Ex Transition Period Entity Ex Transition Period Income Tax Expense (Benefit), Total Tax provision Income Tax Expense (Benefit) Deferred offering costs Deferred Offering Costs Research and Development Research and Development Expense [Member] Payments in equity, amount Development And Manufacturing Services Agreement Payments In Equity Development and manufacturing services agreement payments in equity. 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ASU 2016-02 Accounting Standards Update 2016-02 [Member] Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Purchased for Award Shares Purchased Shares purchased Effect of exchange rate changes on cash and cash equivalents Effect of Exchange Rate on Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Continuing Operations Aggregate Intrinsic Value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value Total funding committed by award, available upon achievement of development milestones Funding Committed By Award Available Upon Achievement Of Development Milestones Funding committed by award, available upon achievement of development milestones. Net Loss Per Share Earnings Per Share, Policy [Policy Text Block] Jefferies LLC Jefferies Limited Liability Company [Member] Jefferies limited liability company. Total assets measured at fair value, Fair Value Cash And Cash Equivalents And Investments Cash and cash equivalents and investments. 2014 Equity Incentive Plan Two Thousand Fourteen Equity Incentive Plan [Member] Two thousand fourteen equity incentive plan. Total other income, net Other Nonoperating Income (Expense) Sale of Stock, Price Per Share Average net Average price Operating expenses: Operating Expenses [Abstract] Property, Plant and Equipment [Abstract] Depreciation, Depletion and Amortization, Nonproduction, Total Depreciation and amortization expense Depreciation, Depletion and Amortization, Nonproduction Subsequent Events [Abstract] Other comprehensive loss: Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract] Follow on public offering Follow On Public Offering [Member] Follow on public offering member. Commitments and Contingencies Disclosure [Abstract] Other Assets, Noncurrent, Total Other assets Other Assets, Noncurrent Number of Options, granted Options granted Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Other accrued expenses Other Accrued Liabilities, Current Common Stock Equity [Text Block] Interest Paid, Excluding Capitalized Interest, Operating Activities Cash paid for interest Non cancelable purchase commitments due in third year. Non Cancelable Purchase Commitments Due In Third Year 2025 Investments, Gross Unrealized Gains Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax Stockholders' Equity Equity, Attributable to Parent [Abstract] Lease Contractual Term [Domain] Earnings Per Share [Abstract] Schedule of Maturities of Lease Liabilities Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block] Indefinite-Lived Intangible Assets, Major Class Name [Domain] Percentage of fair value per share on the grant date Percentage Of Fair Value Per Share On The Grant Date Percentage of fair value per share on the grant date. Loss Contingencies [Table] Loss Contingencies [Table] Equity payment, upper limit Threshold Limit On Equity Payments Threshold limit on equity payments. Aggregate gross proceeds from issuance of common stock Gross Proceeds From Issuance Of Common Stock Gross proceeds from issuance of common stock. Accounting Policies [Abstract] Purchased equipment deposits Purchased Equipment Deposits Current Purchased equipment deposits current. Lessee Lease Description [Table] Lessee, Lease, Description [Table] Vesting percentage for stock options granted, Six months thereafter Share based Compensation Arrangement By Share based Payment Award Award Vesting Rights Six Months Thereafter Percentage Share based Compensation Arrangement By Share based Payment Award Award Vesting Rights Six Months Thereafter Percentage Scenario [Axis] Concentration of Credit Risk and Other Risks and Uncertainties Concentration Risk, Credit Risk, Policy [Policy Text Block] Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Other Assets Other Noncurrent Assets [Member] Number of renewal options Number Of Renewal Options Number of renewal options. Payments in equity, percentage Development And Manufacturing Services Agreement Equity Payments Percentage Development and manufacturing services agreement equity payments percentage. Opearting lease remaining contractual term Lessee, Operating Lease, Remaining Lease Term Earnings Per Share, Basic, Total Earnings Per Share, Basic Net loss per share, basic Commitments and contingencies (Note 6) Commitments and Contingencies Potential funding amount of award to develop vaccine to prevent shingella infections Potential Funding Amount Of Award To Develop Vaccine To Prevent Infections Potential funding amount of award to develop vaccine to prevent infections. Income Statement [Abstract] Commercial Paper, Not Included with Cash and Cash Equivalents Commercial Paper, Not Included with Cash and Cash Equivalents [Member] Commercial Paper Increase or Decrease of Pre-funded Warrant Percentage Not Exceed Increase or Decrease of Pre-funded Warrant Percentage Not Exceed Increase or Decrease of Pre-funded Warrant Percentage Not Exceed Performance-based Awards Performance Shares [Member] Retirement Benefits [Abstract] Operating lease, commencement date Lessee Operating Lease Commencement Date Lessee operating lease commencement date. Number of Options, Vested and expected to vest Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Statistical Measurement Statistical Measurement [Domain] Loss Contingencies [Line Items] Loss Contingencies [Line Items] Net cash used in operating activities Net Cash Provided by (Used in) Operating Activities Lonza DMSA Lonza Limited [Member] Lonza limited. Lonza Ltd. Weighted average grant date fair value, vested and released Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Aggregate Intrinsic Value, Vested Document Period End Date Document Period End Date Statistical Measurement Statistical Measurement [Axis] Commitments and Contingencies Commitments and Contingencies Disclosure [Text Block] Cash paid for operating lease liabilities Operating Lease, Payments Earnings Per Share, Diluted, Total Earnings Per Share, Diluted Net loss per share, diluted Product and Service Product and Service [Domain] Aggregate offering price Sale Of Common Stock Authorized Amount Sale of common stock authorized amount. Fair Value Hierarchy and NAV Fair Value Hierarchy and NAV [Domain] Restricted stock units withheld Restricted stock units withheld Restricted stock units withheld Number of Options, Exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number Funding Arrangement Funding Arrangement [Text Block] Funding arrangement. Pneumococcal Conjugate Vaccine Pneumococcal Conjugate Vaccine [Member] Pneumococcal conjugate vaccine. 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U.S. Treasury Securities US Treasury Securities [Member] Foreign currency transaction gains (losses) Foreign Currency Transaction Gain (Loss), before Tax, Total Gain (Loss), Foreign Currency Transaction, before Tax 2020 Plan and 2014 Plan Two Thousand Twenty Equity Incentive Plan And Two Thousand Fourteen Equity Incentive Plan [Member] Two thousand twenty equity incentive plan and two thousand fourteen equity incentive plan. 2014 Plan, 2020 Plan and 2020 ESPP Two Thousand Fourteen Equity Incentive Plan And Two Thousand Twenty Equity Incentive Plan And Two Thousand Twenty Employee Stock Purchase Plan [Member] Two thousand fourteen equity incentive plan and two thousand twenty equity incentive plan and two thousand twenty employee stock purchase plan. Share based compensation arrangement by share based payment award number of share authorized. 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Over-Allotment Option [Member] Over Allotment Option Increase (Decrease) in Accounts Payable, Total Accounts payable Increase (Decrease) in Accounts Payable Equity [Abstract] Less: Imputed interest Lessee, Operating Lease, Liability, Undiscounted Excess Amount Lessee, Operating Lease, Liability, Undiscounted Excess Amount, Total Less: Imputed interest Granted Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Upfront consideration in cash after agreement date. Upfront Consideration in Cash After Agreement Date Upfront Consideration in Cash After Agreement Date Weighted-average price per share Weighted-Average Exercise Price Per Share, Options exercised Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Cash, Cash Equivalents and Restricted Cash Cash and Cash Equivalents, Policy [Policy Text Block] Agreement termination penalty Agreement Termination Penalty Agreement termination penalty. Equity Components Equity Components [Axis] Non cancelable purchase commitments due in four year. 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Statement of Cash Flows [Abstract] Organization, Consolidation and Presentation of Financial Statements [Abstract] Accumulated Other Comprehensive Income (Loss), Net of Tax, Total Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated other comprehensive loss Weighted average grant date fair value, cancelled Share based Compensation Arrangement By Share based Payment Award Equity Instruments Other Than Options Aggregate Intrinsic Value Cancelled Share based Compensation Arrangement By Share based Payment Award Equity Instruments Other Than Options Aggregate Intrinsic Value Cancelled Deferred Offering Costs Deferred Charges, Policy [Policy Text Block] Offering period Offering Period Offering period. Common stock, par value per share Common stock, par value Common Stock, Par or Stated Value Per Share Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Unrecognized share-based compensation expense, expected to be recognized Long-Lived Tangible Asset Long-Lived Tangible Asset [Axis] Funding period of award to develop universal vaccine to prevent infections caused by Group A Strep bacteria Funding Period Of Award To Develop Universal Vaccine To Prevent Infections Funding period of award to develop universal vaccine to prevent infections. 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Number of Options, forfeited Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Schedule of Potentially Dilutive Securities Excluded From Computation of Diluted Net Loss Per Share Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Proceeds from issuance of common stock from follow-on offering, net of issuance costs Proceeds from issuance of common stock from follow-on offering, net of issuance costs. Proceeds From Issuance Of Common Stock From Follow-On Offering, Net Of Issuance Costs City Area Code City Area Code Cash flows from operating activities: Net Cash Provided by (Used in) Operating Activities [Abstract] Common stock, voting rights Common Stock, Voting Rights Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total Less: accumulated depreciation and amortization Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment General and Administrative Expense, Total General and administrative General and Administrative Expense Weighted Average Number of Shares Outstanding, Basic, Total Weighted Average Number of Shares Outstanding, Basic Weighted-average shares outstanding, basic Summary of Estimated Fair Value of Shares Under Employee Stock Purchase Plan Schedule of Share-Based Payment Award, Employee Stock Purchase Plan, Valuation Assumptions [Table Text Block] Upfront consideration in cash. Upfront Consideration in Cash Upfront Consideration in Cash Amount recorded with respect to the potential future payments above the initial cash cap Guarantor Obligations, Maximum Exposure, Undiscounted Cash flows from financing activities: Net Cash Provided by (Used in) Financing Activities [Abstract] Operating lease, description Lessee, Operating Lease, Description Statement [Table] Statement [Table] Summary of Activity Under Stock Option Plans Share-Based Payment Arrangement, Option, Activity [Table Text Block] Summary of Estimated Fair Value of Employee Stock Options Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Document Fiscal Period Focus Document Fiscal Period Focus Total future undiscounted lease payments Lessee, Operating Lease, Liability, to be Paid Investments Investment, Policy [Policy Text Block] 2024 Lessee, Operating Lease, Liability, to be Paid, Year Two Statement [Line Items] Statement [Line Items] Accrued manufacturing rights expenses Accrued Manufacturing Rights Expenses Antidilutive securities excluded from computation of diluted net loss per share Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Clinical Studies Clinical Studies Clinical studies Subsequent Event [Line Items] Exercise price expire in years form the date of grant Exercise Price Expire In Years Form The Date Of Grant Exercise price expire in years form the date of grant. Pre -funded Warrant exercised Warrant exercised Class Of Warrant Or Right Number Of Securities Called By Each Warrant Or Right Exercised Class of warrant or right number of securities called by each warrant or right exercised. Asset Class Asset Class [Domain] Number of options exercised, excludes options exercised from NPLN. Number Of Options Exercised Excludes Options Exercised From NPLN Exercise of stock options (in shares) Common Stock [Member] Common Stock Common Stock [Member] Change in accounting principle, accounting standards update, early adoption [true false] Change in Accounting Principle, Accounting Standards Update, Early Adoption [true false] IPO-related costs Initial Public Offering Related Cost Initial public offering related cost. Accrued manufacturing expenses Increase Decrease In Accrued Manufacturing Expenses Increase decrease in accrued manufacturing expenses. Cash and Cash Equivalents, at Carrying Value, Ending Balance Cash and Cash Equivalents, at Carrying Value, Beginning Balance Cash and Cash Equivalents, at Carrying Value, Total Cash and cash equivalents Cash and Cash Equivalents, at Carrying Value Other current assets Other Assets, Current Grant receivable on unreimbursed, eligible costs incurred Grants Receivable Aggregate Intrinsic Value, Exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Net amortization (accretion) of premiums (discounts) on investments Accretion (Amortization) of Discounts and Premiums, Investments Prepaid expenses Prepaid Expense, Current Prepaid Expense, Current, Total Office Building [Member] Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Sale of investments Proceeds from Sale of Debt Securities, Available-for-Sale Antidilutive Securities, Name Antidilutive Securities, Name [Domain] Cash Cash [Member] Shares issued Stock Issued During Period, Shares of follow on offering Stock issued during period, shares of follow on offering. Cover [Abstract] Document Fiscal Year Focus Document Fiscal Year Focus Lessee Operating Lease Liability Payments Net Of Lease Incentives Remainder Of Fiscal Year Lessee operating lease liability payments net of lease incentives remainder of fiscal year. Remainder of 2023 Remainder of 2023 Fair value assets transferred out of level 3 Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset, Transfers out of Level 3 Marketable Securities, Realized Gain (Loss), Total Marketable Securities, Realized Gain (Loss) Realized losses on marketable securities Acquired manufacturing rights. Acquired Manufacturing Rights Acquired manufacturing rights Sale of Stock Sale of Stock [Domain] Security Exchange Name Security Exchange Name Long-term Investments, Total Long-term investments Long-Term Investments Term of plan Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period New Accounting Pronouncements Or Change In Accounting Principle [Table] Accounting Standards Update and Change in Accounting Principle [Table] Recently Adopted Accounting Pronouncements New Accounting Pronouncements, Policy [Policy Text Block] Schedule of Common Stock Shares Reserved for Future Issuance Schedule Of Common Stock Shares Reserved For Future Issuance Table [Text Block] Schedule of common stock shares reserved for future issuance. Preferred Stock, Shares Issued, Total Preferred stock, shares issued Preferred Stock, Shares Issued Preferred stock, shares authorized Preferred Stock, Shares Authorized Property, Plant and Equipment, Gross, Ending Balance Property, Plant and Equipment, Gross, Beginning Balance Property, Plant and Equipment, Gross, Total Total property and equipment Property, Plant and Equipment, Gross Unaudited Interim Condensed Financial Statements Unaudited Interim Condensed Financial Statements Policy Policy [Text Block] Unaudited interim condensed financial statements policy. Stock options granted term Stock Options Granted Term Stock options granted term. Weighted-Average Exercise Price Per Share, Options forfeited Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Percentage of defer payments agreed for completion Percentage Of Payments Completion Agreed To Defer Percentage of payments completion agreed to defer. Exercise of stock options Stock Issued During Period, Value, Stock Options Exercised Entity Emerging Growth Company Entity Emerging Growth Company Intrinsic value of the stock options exercised Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value Amendment Flag Amendment Flag Schedule of Accrued Expenses Schedule of Accrued Liabilities [Table Text Block] IPO Initial Public Offering IPO [Member] Investments, Gross Unrealized Losses Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax Accounting Standards Update Accounting Standards Update [Domain] At the market offering At The Market Offering [Member] At the market offering member. Basis of Presentation Basis of Accounting, Policy [Policy Text Block] Cost Reimbursement Sub-Award Agreement Cost Reimbursement Sub Award Agreement [Member] Cost reimbursement sub-award agreement. Purchases of investments Payments to Acquire Debt Securities, Available-for-Sale Leases [Abstract] Total assets measured at fair value, Gross Unrealized Gains Cash And Cash Equivalents And Investments Gross Unrealized Gain Before Tax Cash and cash equivalents and investments gross unrealized gain before tax. Total assets measured at fair value, Gross Unrealized Losses Cash And Cash Equivalents And Investments Gross Unrealized Loss Before Tax Cash and cash equivalents and investments gross unrealized loss before tax. Weighted average grant date fair value, granted Share based Compensation Arrangement By Share based Payment Award Equity Instruments Other Than Options Aggregate Intrinsic Value Granted Share based Compensation Arrangement By Share based Payment Award Equity Instruments Other Than Options Aggregate Intrinsic Value Granted Entity File Number Securities Act File Number Pre-funded warrants to purchase shares Shares Pre-Funded Warrants To Purchase Shares pre-funded warrants to purchase. Automatic renewal period Automatic Renewal Period Automatic renewal period. OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax Unrealized gains (loss) on investments Cash, cash equivalents and restricted cash Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Total Cash, cash equivalents and restricted cash, beginning of period Cash, cash equivalents and restricted cash, end of period Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents Headquarters Facility Headquarters Facility [Member] Headquarters facility. Share-Based Payment Arrangement [Abstract] Shares Available for Future Stock Option Grants Shares Available For Future Stock Option Grants [Member] Shares available for future stock option grants. Issuance costs Temporary Equity Stock Issuance Costs Temporary equity stock issuance costs. Accounts Payable, Current, Total Accounts payable Accounts Payable, Current Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Weighted average grant date fair value, Beginning balance Weighted average grant date fair value, Ending balance Total operating expenses Operating Expenses Non Cancelable Purchase Commitments Due In Second Year Non Cancelable Purchase Commitments Due In Second Year 2024 Expected term (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Entity Address, Address Line Two Entity Address, Address Line Two Preferred stock, $0.001 par value -10,000,000 shares authorized at September 30, 2023 and December 31, 2022; no shares issued and outstanding at September 30, 2023 and December 31, 2022 Preferred Stock, Value, Issued, Ending Balance Preferred Stock, Value, Issued, Beginning Balance Preferred Stock, Value, Issued, Total Preferred Stock, Value, Issued Entity Small Business Entity Small Business Entity Shell Company Entity Shell Company Net Loss Per Share Earnings Per Share [Text Block] Agreement termination description Agreement Termination Description Agreement termination description. Commercial Paper Commercial Paper [Member] Entity Address, Address Line One Entity Address, Address Line One Operating lease rental adjustment Percentage of Operating Lease Rental Adjustments Percentage of operating lease rental adjustments. Cash and cash equivalents, Fair Value Cash and Cash Equivalents, Fair Value Disclosure Antidilutive Securities Antidilutive Securities [Axis] Balance Sheet Details Supplemental Balance Sheet Disclosures [Text Block] Fair value liabilities level 1 to level 2 transfers amount 1 Fair Value Liabilities Level 1 To Level 2 Transfers Amount 1 Other Restricted Stock Units Other Restricted Stock Units [Member] Other Restricted Stock Units [Member] Restricted cash Restricted Cash Restricted Cash, Total Subsequent Event Type [Domain] Issuance costs Issuance costs Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs Risk-free interest rate, Minimum Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum Income Statement Location Income Statement Location [Axis] Unrealized gains (losses) on investments OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment and Tax Risk-free interest rate, Maximum Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum Expected dividend yield Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total Net loss Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Level 2 Fair Value, Inputs, Level 2 [Member] Potential funding period of award to develop vaccine to prevent shingella infections Potential Funding Period Of Award To Develop Vaccine To Prevent Infections Potential funding period of award to develop vaccine to prevent infections. Equity incentive plan, shares issued Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Issued in Period Closing price of common stock Share Price Depreciation, Depletion and Amortization, Total Depreciation and amortization Depreciation, Depletion and Amortization Product and Service Product and Service [Axis] Title of 12(b) Security Title of 12(b) Security Other research and development liabilities current. Other Research and Development Liabilities Current Other research and development Cash and cash equivalents, Gross Unrealized Gains Cash And Cash Equivalents Gross Unrealized Gain Before Tax Cash and cash equivalents gross unrealized gain before tax. Operating lease, extended maturity date Lessee Operating Lease Extended Maturity Date Lessee, operating lease, extended maturity date. Lease Contractual Term [Axis] Operating lease, renewal option Lessee Operating Lease Renewal Option Lessee operating lease renewal option. Percentage of payroll deductions of eligible compensation Share-Based Compensation Arrangement by Share-Based Payment Award, Maximum Employee Subscription Rate Schedule of Financial Instruments Measured at Fair Value on Recurring Basis Fair Value, Assets Measured on Recurring Basis [Table Text Block] Accounting Standards Update Accounting Standards Update [Axis] Other income (expense), net: Other Nonoperating Income (Expense) [Abstract] Prepaid Expenses and Other Current Assets Prepaid Expenses and Other Current Assets [Member] 2020 Equity Incentive Plan Two Thousand Twenty Equity Incentive Plan [Member] Two thousand twenty equity incentive plan. Cash flows from investing activities: Net Cash Provided by (Used in) Investing Activities [Abstract] Potential funding committed by award Potential Funding Committed By Award Potential funding committed by award. Long-Lived Tangible Asset Long-Lived Tangible Asset [Domain] Subsequent Event [Table] Common stock, dividends, per share, declared Common Stock, Dividends, Per Share, Declared Area of office and laboratory space Net Rentable Area Non cancelable Purchase Commitments Due Within One Year Non cancelable Purchase Commitments Due Within One Year Remainder of 2023 Grant E PickeringTrading Arrangement Common Stock Sale Member Grant E PickeringTrading Arrangement Common Stock Sale [Member] Grant E PickeringTrading Arrangement Common Stock Sale Member Due in one to five years Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, after Year One Through Five Lab Equipment Lab Equipment [Member] Lab equipment. San Carlos San Carlos [Member] San Carlos. Lease Termination Date Lease Termination Date Lease termination date. Weighted-Average Remaining Contractual Term (Years), Exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Common Stock, Shares, Outstanding, Ending Balance Common Stock, Shares, Outstanding, Beginning Balance Common stock, shares outstanding Common Stock, Shares, Outstanding Risk-free interest rate Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Equity Incentive Plans Share-Based Payment Arrangement [Text Block] Research and development expense to related party Research And Development Expense To Related Party Research and development expense to related party. Additional funding committed by award Additional Funding Committed By Award Additional funding committed by award. Income Statement Location Income Statement Location [Domain] Weighted-Average Exercise Price Per Share, Options granted Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Document Type Document Type Incentive stock option granted to employees owning percentage of shares of common stock Incentive Stock Option Granted To Employees Owning Percentage Of Shares Of Common Stock Incentive stock option granted to Employees Owning percentage of shares of common stock. Net Cash Provided by (Used in) Investing Activities Net cash (used in) provided by investing activities Document Quarterly Report Document Quarterly Report Available for issuance of shares increased Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Increase In Available For Grant Share based compensation arrangement by share based payment award number of shares increase in available for grant. Counterparty Name Counterparty Name [Domain] Net Income (Loss) Available to Common Stockholders, Basic, Total Net loss (in thousands) Net Income (Loss) Available to Common Stockholders, Basic Cancelled Cancelled Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Agreement expiration date Commercial Manufacturing and Supply Agreement Expiration Date Commercial manufacturing and supply agreement expiration date. Net cash provided by financing activities Net Cash Provided by (Used in) Financing Activities Options and Restricted Stock Units Available for Grant, Additional shares authorized Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Additional Shares Authorized Additional shares authorized Entity Filer Category Entity Filer Category Supplemental disclosure of non-cash investing activities: Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract] Balance Sheet Location Balance Sheet Location [Domain] Increase (Decrease) in Accrued Liabilities, Total Accrued expenses Increase (Decrease) in Accrued Liabilities Accrued Liabilities, Current [Abstract] Short-term Investments, Total Short-term investments Short-Term Investments Asset Class Asset Class [Axis] Purchases of property and equipment recorded in accounts payable and accrued expenses Capital Expenditures Incurred but Not yet Paid Warrants Disclosure [Text Block] Warrants. Pre-Funded Warrants Total liabilities Liabilities Schedule Of Property Plant And Equipment [Table] Property, Plant and Equipment [Table] Accrued payment Accrued Payment Accrued payment Asset Impairment Charges, Total Asset impairment charges Asset Impairment Charges Total stockholders' equity Beginning balance Ending balance Equity, Attributable to Parent Net loss Interest Expense, Total Interest Expense Interest Expense Corporate Debt Corporate Debt Securities [Member] Statement of Financial Position [Abstract] Basis of Presentation and Summary of Significant Accounting Policies Basis of Presentation and Significant Accounting Policies [Text Block] Schedule of Non-cancelable Purchase Commitments Related to Raw Materials Schedule Of non-cancelable purchase commitments related to raw materials [Table Text Block] Schedule Of non-cancelable purchase commitments related to raw materials [Table Text Block] Weighted Average Number of Shares Outstanding, Diluted, Total Weighted Average Number of Shares Outstanding, Diluted Weighted-average shares outstanding, diluted Changes in operating assets and liabilities: Increase (Decrease) in Operating Liabilities [Abstract] Amortization of operating lease right-of-use assets Operating Lease, Right-of-Use Asset, Periodic Reduction Public offering price per share Shares Issued, Price Per Share Investments, Amortized Cost Debt Securities, Available-for-Sale, Amortized Cost Weighted-average remaining lease term (in years) Operating Lease, Weighted Average Remaining Lease Term Defined Benefit Plan, Net Periodic Benefit Cost (Credit), Total Defined Benefit Plan, Net Periodic Benefit Cost (Credit) Contributed to retirement plan Company contributions Employees purchase shares of common stock of lower of fair market value Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent Use of Estimates Use of Estimates, Policy [Policy Text Block] Assumed lease rental payment Assumed lease rental payment. Income Taxes Income Tax Disclosure [Text Block] Remaining liabilities related to early exercised shares Remaining Liabilities Related To Early Exercised Shares Remaining liabilities related to early exercised shares. Weighted-Average Exercise Price Per Share, Beginning Balance Weighted-Average Exercise Price Per Share, Ending Balance Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Schedule of Computation of Basic and Diluted Net Loss Per Share Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Leasehold Improvements Leasehold Improvements [Member] Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Funding Arrangement [Abstract] Funding arrangement. Fair Value Disclosures [Abstract] Percentage of outstanding number of shares Share-Based Compensation Arrangement by Share-Based Payment Award, Percentage of Outstanding Stock Maximum Fair Value Hierarchy and NAV Fair Value Hierarchy and NAV [Axis] Measurement Frequency Measurement Frequency [Domain] CARB-X Agreement Combating Antibiotic Resistant Bacteria Biopharmaceutical Accelerator Agreement [Member] Combating antibiotic resistant bacteria biopharmaceutical accelerator agreement. Other Liabilities Other Noncurrent Liabilities [Member] Payments to Acquire Property, Plant, and Equipment, Total Purchases of property and equipment Payments to Acquire Property, Plant, and Equipment Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Aggregate Intrinsic Value, Nonvested Weighted average grant date fair value, Beginning balance Weighted average grant date fair value, Ending balance Redeemable Convertible Preferred Stock Redeemable Convertible Preferred Stock [Member] Vested and released Number of restricted stock units vested Vested Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Stock Issued During Period, Shares, New Issues Issuance of common stock, shares Common stock shares sold Employee-related Liabilities, Current, Total Accrued compensation Employee-related Liabilities, Current Operating lease rent expense recognized Operating Lease, Expense Income Tax Disclosure [Abstract]